Which medication might be added to the regimen of a client receiving isoniazid?

Which medication might be added to the regimen of a client receiving isoniazid?

• A. Niacin
• B. Pyridoxine
• C. Gabapentin
• D. Cyanocobalamin

Answer: (B)

Isoniazid is a commonly used antibiotic for the treatment of tuberculosis, but it can lead to vitamin B6 deficiency (pyridoxine deficiency) in some patients. This deficiency occurs because isoniazid can interfere with the metabolism of vitamin B6, which is vital for numerous physiological functions including protein metabolism and the synthesis of neurotransmitters. Adding pyridoxine to the treatment regimen helps prevent or treat this deficiency, thus mitigating potential side effects such as peripheral neuropathy. Peripheral neuropathy can be particularly concerning in patients who may have additional risk factors such as diabetes or alcoholism. By ensuring adequate levels of pyridoxine, the healthcare provider safeguards against these complications, thereby improving the overall safety and effectiveness of the tuberculosis treatment. The other medications listed do not address the specific vitamin B6 deficiency associated with isoniazid use and would not provide the protective benefits that pyridoxine offers in this context.

Isoniazid is a commonly used antibiotic for the treatment of tuberculosis, but it can lead to vitamin B6 deficiency (pyridoxine deficiency) in some patients. This deficiency occurs because isoniazid can interfere with the metabolism of vitamin B6, which is vital for numerous physiological functions including protein metabolism and the synthesis of neurotransmitters.

Adding pyridoxine to the treatment regimen helps prevent or treat this deficiency, thus mitigating potential side effects such as peripheral neuropathy. Peripheral neuropathy can be particularly concerning in patients who may have additional risk factors such as diabetes or alcoholism. By ensuring adequate levels of pyridoxine, the healthcare provider safeguards against these complications, thereby improving the overall safety and effectiveness of the tuberculosis treatment.

The other medications listed do not address the specific vitamin B6 deficiency associated with isoniazid use and would not provide the protective benefits that pyridoxine offers in this context.